Strophanthus hispidus: its Natural History, Chemistry, and Pharmacology

Natural Alkamides: Pharmacology, Chemistry and Distribution

Alkamides are a broad and expanding group of bioactive natural compounds found in at least 33 plant families. Despite the relatively simple molecular architecture of alkamides (fig. 1), these natural products show broad structural variability and an important range of biological activities, such as immunomodulatory, antimicrobial, antiviral, larvicidal, insecticidal, diuretic, pungent, analgesi...

Antimicrobial, Antioxidant, and Wound Healing Properties of Kigelia africana (Lam.) Beneth. and Strophanthus hispidus DC.

Microbial infections of various types of wounds are a challenge to the treatment of wounds and wound healing. The study was to investigate antimicrobial and antioxidant properties of methanol leaf and stem bark extracts of Kigelia africana and methanol leaf and root extracts of Strophanthus hispidus and also to determine wound healing properties of the extracts. The antimicrobial activities of ...

Terminalia Arjuna: Its Chemistry, Pharmacology and Therapeutic Action

Combinatorial chemistry and contemporary pharmacology.

Both solid- and liquid-phase combinatorial chemistry have emerged as powerful tools for identifying pharmacologically active compounds and optimizing the biological activity of a lead compound. Complementary high-throughput in vitro assays are essential for compound evaluation. Cell-based assays that use optical endpoints permit investigation of a wide variety of functional properties of these ...

Chemistry and pharmacology of benzodioxanes

Benzodioxane represents a series of synthetic and natural compounds of considerable medicinal importance. Compounds containing dioxane ring systems exhibited different biological activities such as antihepatotoxic, -adrenergic blocking agent, neuroleptic, anti-inflammatory, hypolipidemic and D 2 antagonist/5-HT 1A partial agonist activity. The literature concerning chemistry of benzodioxanes c...